Proteome Dynamics and Proteome Function of Cardiac 19S Proteasomes
نویسندگان
چکیده
منابع مشابه
Proteome dynamics and proteome function of cardiac 19S proteasomes.
Myocardial proteasomes are comprised of 20S core particles and 19S regulatory particles, which together carry out targeted degradation of cardiac proteins. The 19S complex is unique among the regulators of proteasomes in that it affects both the capacity and specificity of protein degradation. However, a comprehensive molecular characterization of cardiac 19S complexes is lacking. In this inves...
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ژورنال
عنوان ژورنال: Molecular & Cellular Proteomics
سال: 2011
ISSN: 1535-9476
DOI: 10.1074/mcp.m110.006122